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Air pollution increases lung cancer risk in non-smokers

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  • A recent study highlights air pollution as a key factor in the rising rates of lung cancer, particularly adenocarcinoma, in non-smokers, especially women.
  • The study emphasizes that regions with high pollution levels, like South-East Asia, are experiencing the most significant increase in lung cancer cases among non-smokers.
  • Experts call for urgent global action to reduce air pollution and address its growing impact on public health, particularly in high-risk areas.

[WORLD] Recent research has revealed a startling connection between air pollution and an increase in lung cancer cases, particularly among non-smokers. The study, published in the Lancet Respiratory Medicine journal, highlights the significant role of environmental factors, particularly air pollution, in the rise of lung cancer, specifically adenocarcinoma, in non-smokers. This is particularly troubling for women and populations in South-East Asia, where air pollution levels are often at their highest.

The Link Between Air Pollution and Lung Cancer

Lung cancer remains one of the most prevalent cancers worldwide, with approximately 2.5 million new cases diagnosed in 2022. Traditionally, lung cancer has been strongly associated with smoking, but recent trends show a significant rise in cases among non-smokers. This shift has raised alarms about the role of environmental pollutants in fueling this increase.

A particularly alarming aspect of the study is the rise of adenocarcinoma, the most common subtype of lung cancer in non-smokers. This subtype has seen a sharp increase in the past few decades, especially among women and in certain regions like South-East Asia. According to the study, "Air pollution can be considered an important factor that partly explains the emerging predominance of adenocarcinoma, which accounts for 53-70% of cases of lung cancer among people who have never smoked worldwide."

The study’s findings are consistent with the rising global concern about air pollution's effects on health. As smoking rates decline globally, the proportion of lung cancer cases among non-smokers has steadily increased, with women and people from East Asia bearing the brunt of this shift.

The Rising Toll on Non-Smokers

In many countries, smoking rates have significantly dropped, especially among women. However, the prevalence of lung cancer in non-smokers is on the rise, with the disease becoming the fifth leading cause of cancer-related deaths worldwide. According to the study, "Lung cancer in people who have never smoked is estimated to be the fifth leading cause of cancer-related mortality worldwide, occurring almost exclusively as adenocarcinoma and most commonly in women and Asian populations."

This shift highlights a disturbing trend: while the battle against smoking-related cancers continues to make strides, non-smoking-related lung cancer is becoming an ever-growing concern. The study found that the rise of lung cancer in non-smokers is particularly evident in regions with high levels of air pollution.

The Role of Air Pollution

One of the critical findings of this research is the relationship between air pollution and the rise in lung cancer cases, particularly adenocarcinoma. The highest levels of lung cancer linked to air pollution were detected in East Asia, with China being one of the hardest-hit regions. As noted in the study, "The highest levels of adenocarcinoma linked to air pollution were detected in East Asia, particularly China."

Air pollution comes in many forms, including outdoor pollutants like vehicle emissions and industrial pollution, as well as indoor pollutants such as household burning of solid fuels for heating and cooking. The study suggests that the use of solid fuels in households, particularly in China, could be a significant factor in the higher rates of lung cancer among women who do not smoke. "Exposure to household burning of solid fuels for heating and cooking could be a causal factor of lung cancer among Chinese women non-smokers," the study authors explained.

A Growing Crisis in South-East Asia

South-East Asia, with its rapidly growing urban populations and high pollution levels, is witnessing a worrying rise in lung cancer cases, particularly in non-smokers. The study underscores that "women in South-East Asia, where air pollution is a significant problem, are particularly affected by the increasing rates of lung cancer." These regions often face severe air pollution, which exacerbates the health risks faced by the population.

The findings of the study suggest that tackling air pollution is crucial in reducing the burden of lung cancer in these high-risk regions. Addressing both outdoor and indoor air pollution could play a key role in preventing the rise in lung cancer cases among non-smokers, especially women.

The Need for Global Action

The study’s findings are a call to action for governments, health organizations, and individuals alike. While efforts to reduce smoking continue, the rise of lung cancer in non-smokers due to air pollution demands urgent attention. Governments worldwide must prioritize policies that target air pollution reduction, particularly in regions most affected by environmental contaminants. "As smoking prevalence continues to decline in many countries worldwide, the proportion of lung cancer in people who have never smoked has increased," the researchers noted, emphasizing the need for greater attention to environmental factors in cancer prevention.

At the individual level, people living in highly polluted areas should be made aware of the risks posed by exposure to air pollutants. Lifestyle changes, such as using air purifiers in homes and reducing outdoor exposure during high pollution days, could help reduce some of the risks associated with air pollution.

The findings of this study underscore a critical shift in the global landscape of lung cancer. While smoking has historically been the leading cause of lung cancer, air pollution is now emerging as a significant risk factor, particularly for non-smokers. The rising incidence of adenocarcinoma in women and in regions like South-East Asia serves as a stark reminder of the need to address environmental health issues on a global scale.

As we continue to combat the health impacts of smoking, the rising threat posed by air pollution must not be overlooked. Policy changes, public health campaigns, and individual actions must all work together to reduce air pollution levels and mitigate its harmful effects on lung health. Until these measures are put in place, the global rise in lung cancer among non-smokers is likely to continue, with devastating consequences for millions of people worldwide.


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